About Application Protocols, Authenticated Connections, and Domain Controllers : About SMB2 and SMB3
  
About SMB2 and SMB3
SMB2/3 acceleration optimizes file sharing among Windows clients and servers. Encryption requires that SMB signing is enabled on the server-side SteelHead. Latency and bandwidth optimization for encrypted, SMB-signed traffic is supported.
SMB 3.02 is qualified with signed, unsigned, and encrypted traffic over IPv4 and IPv6. Authenticated connections between a server-side SteelHead and a domain controller are only supported over IPv4.
Delegation mode signing is deprecated.
For details on SMB specifications, go to http://msdn.microsoft.com/en-us/library/cc246482.aspx.
About Application Protocols, Authenticated Connections, and Domain Controllers
About secure traffic authentication
About SMB2 and SMB3 settings
About SMB signing
Viewing SMB connections
About Windows domain authentication