SteelHeadā„¢ Deployment Guide : IPv6 : Protocol Support
  
Protocol Support
Optimization for TCP-over-IPv6 traffic supports data reduction for any connection. In addition to data reduction, the following protocols have application streamlining support:
  • FTP
  • SSL
  • HTTP
  • MAPI
  • Encrypted MAPI
  • SMB
  • For more information about protocol support, see the SteelHead Deployment Guide - Protocols and the Riverbed Command-Line Interface Reference Manual.