Configuring Storage : Configuring REST API Access : Best Practices
  
Best Practices
•  Use one pool manager for all Cores in a logical cluster; make the cluster a single pool.
•  Consider using different pool managers for different clusters, such as Finance, Legal, and so on.
•  If hostnames are used for manager and members, DNS resolution must work. (Hostname entries can be added to manager and members through Configure > Networking: Host Settings to ensure that hostnames resolve correctly.)
•  Be sure to give the pool a recognizable name. When reviewing a member’s Edit Pool page, the user sees the pool name, and thereby knows what the pool is used for.
•  Riverbed recommends that one failover peer be the manager of the other peer. It gives the manager more control over the peer than the failover connection does when both peers are up and running.